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KMID : 1101320060380010059
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Korean Journal of Clinical Laboratory Science
2006 Volume.38 No. 1 p.59 ~ p.64
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Preparation and Clinical Application of pH-ISE(Ion Selective Electrode) Based on Tribenzylamine Ionophore
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Cho Dong-Hoe
Park Chung-Oh
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Abstract
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The pH-ISE(ion selective electrode) based on tribenzylamine as a hydrogen ion carrier was prepared and its electrochemical characterization was studied. It responded linearly to hydrogen ions in the range of pH 3.1 - pH 11.0 and the Nernstian slope showed 55.0 mV/pH (at 20 ± 0.2℃), it also showed a fast response time of 8 sec. When it was directly applied to human blood(pH 6.0-8.5), we could get the same satisfying results. A good reproducibility and stability were shown with the precision of 2 mV (±0.1). The pH-ISE based on tribenzylamine exhibited biocompatibility in clinical applications.
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KEYWORD
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ionophore, ISE, solid contact electrode, tribenzylamine, hydrogen ion sensor
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